ICD-10-CM Diagnosis Code A04.1: Enterotoxigenic Escherichia coli infection

A04.1

A04.1 is a billable and specific ICD-10-CM code. Accurate coding of A04.1 ensures proper diagnosis, effective treatment, and correct reimbursement.

This guide provides details of its use, official guidelines, and historical background.

ICD-10-CM Code For Enterotoxigenic Escherichia coli infection

ICD-10-CM Diagnosis Code for Enterotoxigenic Escherichia coli infection is A04.1.

It is a type of Escherichia Coli bacteria and one of the leading bacterial causes of diarrhea in developing countries especially among children.

Proper documentation using A04.1 ensures patients receive appropriate care and enables accurate healthcare reimbursement.

Synonyms

  • E coli enterotoxigenic enteritis
  • Escherichia coli enterotoxigenic enteritis

History Background of ICD-10-CM Diagnosis Code A04.1

The ICD-9-CM system, first introduced in 1979, provided the initial framework for coding diseases and health-related conditions in the United States. 

The ICD-9-CM Diagnosis code for Enterotoxigenic Escherichia coli infection is 008.02. This coding remained consistent from 1979 to 2015.

While the ICD-9-CM system offered a basic approach to disease classification, modern healthcare needs more detail and specificity. 

To address this, the ICD-10-CM system was launched in 2015, introducing a more comprehensive and accurate coding structure. 

The transition from ICD-9-CM to ICD-10-CM significantly improved the ability to document and analyze conditions caused by Enteropathogenic Escherichia coli infection.

The 2025 edition of ICD-10-CM A04.1 became effective on October 1, 2024.

YEARCODEDESCRIPTION
2020A04.1No Change
2021A04.1No Change
2022A04.1No Change
2023A04.1No Change
2024A04.1No Change
2025A04.1No Change

Symptoms of Enterotoxigenic e. coli 

  • Watery diarrhea
  • Stomach cramps
  • Vomiting

Symptoms can appear as soon as 10 hours after infection but can take up to 72 hours. They usually last less than five days but can last longer.

Other symptoms: Headache, low-grade fever, nausea, and loss of appetite. 

How Enterotoxigenic e. coli Infection is Caused

Enterotoxigenic E. coli (ETEC) is caused by:

  • Contaminated food
  • Contaminated water
  • Person-to-person contact

Other ICD-10-CM Diagnosis Codes in A04

ICD-10-CM code A04 | Other bacterial intestinal infections has following sub categories including A04.1 :

  • A04 Other bacterial intestinal infections
  • A04.0 Enteropathogenic Escherichia coli infection
  • A04.1 Enterotoxigenic Escherichia coli infection
  • A04.2 Enteroinvasive Escherichia coli infection
  • A04.3 Enterohemorrhagic Escherichia coli infection
  • A04.4 Other intestinal Escherichia coli infections
  • A04.5 Campylobacter enteritis
  • A04.6 Enteritis due to Yersinia enterocolitica
  • A04.7 Enterocolitis due to Clostridium difficile
  • A04.71 recurrent
  • A04.72 not specified as recurrent
  • A04.8 Other specified bacterial intestinal infections
  • A04.9 Bacterial intestinal infection, unspecified

Final Thoughts

Proper coding of A04.1 is vital for diagnosing and managing Enteropathogenic Escherichia coli infection. Understanding its symptoms, causes, and coding guidelines ensures accurate documentation and better patient care. This code supports effective healthcare management and ensures proper reimbursement.

About Author
content writer
Dr. Sehrish Bano, CPB & CPC

As a certified professional in both billing and coding, I specialize in streamlining healthcare revenue cycles and ensuring accurate claim submissions. With more than five years of experience serving the healthcare industry in the USA, I bring expertise in coding accuracy, compliance, and reimbursement optimization. My work focuses on reducing errors, improving efficiency, and supporting providers in delivering quality care without administrative hurdles. I am committed to helping healthcare organizations achieve financial stability and compliance through reliable billing and coding practices.

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